Pfizer's Smoking Cessation Drug Gets FDA Approval
> 5/11/2006 12:34:34 PM

For the first time in nearly a decade, there will be a new drug to help those who are hopelessly addicted to cigarettes. The addiction to cigarettes can be one of the strongest known addictions, and this new treatment, known as Chantix works on breaking the addiction in new ways.

From the company's press release:
Chantix is unique because it is specifically designed to partially activate the nicotinic receptor and reduce the severity of the smoker's craving and the withdrawal symptoms from nicotine. Moreover, if a person smokes a cigarette while receiving treatment, Chantix has the potential to diminish the sense of satisfaction associated with smoking. This may help to prevent the cycle of nicotine addiction.

As with previous smoking cessation treatments, a commitment to quitting is still a very large part of successfully leaving cigarettes behind for good. The clinical trials testing Chantix showed that using the drug one in five smokers remained smoke free a year later. Clearly there is a great deal of value in investigating this new treatment, and it would seem that there is some room for improvement, which will more than likely come in the form of finding a complimentary therapy regimen to accompany the medication.

Comments

I have a problem with anxiety. I take 2 mg of Xanax XR per day. Seems to work O.K. When I took my first dose of Chantix, about an hour later, I became extremely anxious -- close to a panic attack. I knew it had to be the Chantix. The next day, I tried taking 1/2 of the .5mg dose. That also made me feel extremely anxious, but not so bad and the effects wore off faster. The third day, I tried another .5mg dose and then went to a friends NASCAR party. I had to leave. I couldn't handle it. There was too much going on around me. Too much input. I felt if I didn't get out of there, I was going to have a panic attack.Have there been any other people that have complained of this side effect?
Posted by: Lori 2/19/2007 2:03:16 AM

The most common side effects of Chantix are nausea, changes in dreaming, constipation, gas and vomiting.When I tried to give up smoking before using Chantix, I would feel anxious, Chanix actually in my case reduced the anxiety... now been smoke free 3 months.
URL: www.campaign143.org
Posted by: chanix 2/22/2007 2:24:32 AM

I didn't understand for nearly 20 years that antidepressants for some people actually make you depressed. Now you will see disclaimers that this or that antidepressant can cause suicidal urges in those 17 and younger. (they say 17 and younger because once you are 18 you are on your own legally) So yes I do believe that Chantix can cause anxiety and I was on it and got the stomach flu and stopped it abruptly because it already made me want to vomit, so I experienced withdrawl on top of the stomach flu. I believe it is as any other mind altering drug, one that is not for everyone, can indeed cause anxiety, increased depression and look out for that withdrawl if you stop it suddenly, which of course you should not do but I was throwing up at the time and couldn't have kept it down if I wanted to. It's a drug that alters the chemistry of your brain, be careful. Not all of us can tolerate it and frankly I think we will hear more and more stories like yours and mine as people desperate to quit smoking find themselves either addicted to their "cure" or suffering side effects way beyond those listed by the manufacturer.
Posted by: Andrew 4/3/2007 11:35:33 AM

Chantix?!?! I used Chantix for 4 months and have been happily smoke free; but...nausea morning and night after taking the pill, I happily dealt w/ a little nausea. Now eight days off Chantix and I'm concerned that I'm going crazy or depression related to Chantix has set in!
Posted by: Annette 4/10/2007 5:12:29 AM

Just be careful.....I was on Chantix for 2 months and then started to notice a bit of depression. I already take 12.5 Mg of Paxil per day. I was taking the 2 mg. a day of the Chantix. I tapered myself down to .5 mg a day of Chantix. At the same time I was moving to a new home, off work for a week and had family come in to visit. All of a sudden 1 day I got up and could not quit crying. The feeling in my stomach was as if someone close to me had passed away. I went off the Chantix completely and contacted my doctor. She increased my Paxil to 25 mg a day. This was 2-1/2 weeks ago. I am just now starting to feel back to normal. I came close to checking myself into the hospital for severe depression. Thank God I have a very supportive husband and very supportive family and friends. I never want to feel that bad again. The good side is that I am still NOT smoking. But, I suggest that if you have any anixiety or depression in your history you may want to rethink the Chantix.
Posted by: Donna 4/16/2007 9:14:43 AM

I took chantix for about 4 months and I experienced very high levels of anxiety and depression. I stopped using chantix immediatly after a suicide attempt due to extreme anxiety. This drug is new, very little in the way of long term effects as well as short term effects have been studied. I would urge others to discontinue use if you experience any anxiety or depressoin and quite smoke by other means.
Posted by: Deborah 4/21/2007 1:08:34 AM

this is my second time on chantix. The first time I lasted 2 weeks, but I felt like I was smoking more. I also became nauseous and anxious. This time I have only been on it for six days and I am definately going off of it as of tonight because the last 2 days I have become very depressed and crying for no reason. And what a terrible headache I have had. I already take zoloft and I feel like the chantix is counter-acting it.
Posted by: Debbi 5/6/2007 6:19:31 AM

I took my first dose today after leaving the doctor's office. I've had extreme anxiety ever since i took it. I've had extreme anxiety in the past, but now feel like my stomach is hot and bloaty, making me panic.. i am actually on here searching for support. i want to quit smoking. i am 40 yr old male smoked since 15 yrs old.
Posted by: john 5/16/2007 10:03:35 AM

Istarted on chnatix in January 07,I took it for 2 months and have been smoke free since a week after I started the drug. However My wife and family have noticed a change in my personality since then.They say,and I agree,that I am very short tempered and have no patience whatsoever.Has anyone else experienced this?
Posted by: jamesashanks 5/17/2007 6:13:43 AM

I have severe sx's 6 wks later. While on Chantrex I had severe dreams but worse was feeling like a Zombie all day(lethargic, drowsy, fatigues, lack of interest etc). I quit after only one month and am still smoke free but still have all the terrible feelings of depression and lethargy one and a half months later. Has anyone experienced this continued problem???
Posted by: Jerry S. 5/19/2007 4:08:14 AM

Like everyone else who has posted a comment on this page, I too took Chantix to quit smoking and have stopped it because of it's side effects. I have been smoke free for a little over 3 weeks, which is great, but I had to quit taking the Chantix because it was making me extremely nauseous, especially at night. I was also experiencing bouts of depression and crying for no particular reason, as well as drowsiness, fatigue, and lack of interest in those things that used to interest me. I stopped taking Chantix 1 week ago and I have been going crazy. I can't sleep at night, which makes me take naps after work because I can't function anymore. I have been crying and craving a cigarette worse now than the day after I quit. I don't know what to do, but I think a phone call to my doctor is in order. I have dealt with depression before, so I may need an antidepressant to help me through this? I don't know...all I know is that I can't start smoking again...it would disappoint too many of my friends and family, but most of all, it would disappoint me. I guess what I'm trying to say to all those whom are facing the same demons as me, hang in there...there has to be an answer that we simply don't see.
Posted by: Amy C. 5/22/2007 6:36:53 AM

Hi Everyone...I started on Chantrix at the end of January this year (2007) and as with any medication found I had to be careful when I took it....If I took it on an empty Stomach I would get dizzy spells and stomach pains...so anyone starting this medication should eat before taking, and maybe the anxiety you are feeling could be from other depressant medication you are taking....because aside from a mild case of stomach ache I tolerated Chantrix and have been Smoke Free since starting the medication in January.... I would highly recomend this medication to anyone over the patch....Lora
Posted by: Lora J 5/30/2007 3:17:55 AM

I'm glad to see I'm not the only one feeling a little "off center". I took chantix for 2 months but have decided not to go for the third cycle. My main complaint is that I've just felt kinda dumb on the stuff. Like I'm in a fog all day long....really hope it's not permanent. I've also been feeling anxiety.....mostly in the early morning.....as in an hour or 2 before I normally wake up. I'll wake up with no memory of any dream, but feel really stressed and worried. The anxiety usually passes once I'm up and moving around.
Posted by: Dominique 5/31/2007 7:38:10 AM

I am glad to find that there are others that are experiencing side effects. I am sorry for all of you, don't get me wrong. I started to take Chantix in Feb and successfully quit smoking before my quit date. I was very happy about this, after another 5 weeks on Chantix I decided to quit taking it because of the nausea. I am still smoke free but have lost all control over my psyche. I either scream or cry, I panic, I can't sleep but am exhausted. I finally got on cymbalta and xanax which take the edge off and I don't cry for a complete 20 hours, but I am still good for an hour or two a day. Not for any reason, either. I feel like I am having a constant out of body experience, I see a psycho woman screaming at a my kids until she crys but I can't break through to tell her to lay-off! I stopped taking the stuff in April and it is now June--- I have to be medicated to function. Something is wrong!!!!!
Posted by: rms 6/1/2007 11:42:20 AM

I too am glad to find out that I'm not alone in my Chantix experience. After 6 days on it, I became depressed. I have a history of depression, but it's been successfully treated for some time now with Lexapro. I called my doctor, who said to stop taking it immediately. But the next 3 days were hell. I cried almost constantly, for no reason. For the first time ever, I began to think of ways to end my life. Had I had a convenient and sure-fire way to do it, I think I might have. It's day 5 since stopping, and I'm just now feeling myself again. I believe - and hope - that the FDA will eventually specifically state that Chantix should not be taken by anyone with a history of depression. I won't be surprised if we eventually learn that it is linked to suicide. I am horrified at what it did to me, but grateful that nothing happened. It did, however, greatly decrease my desire to smoke.
Posted by: Karen 6/4/2007 8:52:37 AM

I would like to add that the FDA's web site has a form to fill out to report adverse events from medications, etc. I would strongly suggest that anyone who has suffered adverse events from Chantix use this form and report it to the FDA. I did.
Posted by: Karen 6/14/2007 6:21:44 AM

This stuff is horrible and i've not be treated for depression of any type. Never had a problem until chantix. Not only am i sure it will be linked to suicide, i can also see it pulled from the market.
Posted by: anon 6/19/2007 12:06:10 PM

My ex-wife committed suicide on June 5th. We found Chantix in her nightstand with 4 doses gone. She had been diagnosed with bipolar and was taking anti-depressants. Are there any warnings from Phizer on mixing Chantix with anti-depressants or people with bipolar? I thought her bipolar had been under control for the past 5 years....now this.
Posted by: Leroy 6/23/2007 6:14:13 AM

My husband and I were on Chantix for 13 days. With ABSOLUTELY NO PRIOR MENTAL HEALTH ISSUES he tried to take his life on 6/16/2007. Fortunaltey I was home and was able to get him breathing again and get an ambulance there. He was lifeflighted and spent 2 days in ICU, one and half days in a medical ward and then 36 hours in the crisis center. Our state has a mandatory 72 hour hold on suicides, yet they let him go home after only 36 hours because the doctor stated that he had no prior history and was not a threat to himself. He maintains that he would have never done this and is shocked and upset that this happened. He has lost one day prior and 4 days after the event. As I stated above, he had no prior history of depression. So, people that have a prior history need to be doubly aware of the side effects taht may happen. It is scary what can happen. I was on Chantix also, and suffered no adverse reaction, but I am not on it now and I am urging anyone to be very cautious before they take it. Pfizer states in their patient information sheet that in rare cases it may casue suicidal ideation, yet they never define what rare, infrequent, or frequent mean. I strongly urge anyone that has had an adverse reaction to Chantix, please go the FDA website and file an adverse reaction form. The only way that Pfizer will take notice is if the government is aware of what is going on and makes them place warnings on the packaging. As I read these postings, I just get ill how close I came to being a tragedy that could have been avoided. If you are on it or know anyone on it, please make them aware or be aware of yourself, so that if there are changes seek help immediatly!
Posted by: Deanna 6/25/2007 2:44:12 AM

I just started on Chantix today and know that I'm in a depressed state prior to starting. After reading these comments I'm scared that I'll have problems. I talked with two people that have taken the drug, quit smoking for months and haven't had any side effects related to depression. I'm a bit disappointed that it didn't go through the entire regular rig-a-ma-roll with FDA and wonder if enough testing has been done to ensure it is safe.
Posted by: Fran 6/27/2007 2:44:09 AM

I started Chantrex in Feb 07. Not only did I quit smoking; also drinking. When I fell off the program the 1st of May my addictions seem worse than ever for drinking and smoking and I am depressed. My sex drive when to zero immediatley when I started the prescritpion and 4 months later is still zero. My employees noticed a suggnificant change in my personality also. It seemed like the longer I was on the drug I could not keep up with day-to-day activities as usual. Had alot of projects started and got aggriavted that I there was not enough time to do everything. I quit Chantex do to a family members health and needed a break after I left the hospital to visit them the 1st of May. Since then I was considering going back on Chantrex again, but I am so more addited to my bad habits now than ever. I am glad that I saw this posting. I have also always dealt with depression, but do not take anything for it.
Posted by: Brenda 6/29/2007 4:08:56 AM

Hi. I also started taking Chantix on 5/25/07 and am going off of it as of today. I just do not feel like myself and am also having increased anxiety and panic attacks (and more of them) and I am very edgy and irratible. I find myself nitpicking at my husband for no reason and that's just not me. Thank goodness he's a wonderful human being and understands what I am going through. I did quit smoking on the Chantix (after 33 years and hopefully can stay off of them) but I do not like the side effects that are not mentioned to any degree on the insert of the meds. I think Pfizer needed to do more research on the side effects of Chantix before they released it to the public.
Posted by: Ann 6/30/2007 11:09:15 AM

Hi. I took Chantix for about 2 1/2 months and weaned myself off. I felt great on the medicine unti i started to come down on the dosage and then off of it. I have been experiencing severe depression ever since i stopped taking the medicine. I am still smoke free but if my doctor doesn't come up with a solution I won't be smoke free for long. I have a history of depression that has been well maintained for several years. Now i am experiencing a depression I couldn't have ever imagined. Its like an out of body experience. I can't wait to feel like myself again. This depression is effecting everything and everyone in my life.
Posted by: Kelly 7/2/2007 12:31:23 PM

I experienced severe depression, suicidal thoughts, agitation, crying for no reason, a complete inability to concentrate...etc. after being off Chantix for 2 days. I only took it for 6 days, but had to quit because of the joint pain. 6 months later, I am still having issues with memory and thinking clearly. I have been put on a combo of 2 antidepressants and something for panic which has helped my moods. Very upset about this, and don't know what else I can do to get back to the person I was before I took Chantix.
Posted by: Brenda 7/4/2007 1:10:28 AM

This medication may be a helpful tool for some, but be careful!!! My experience with Chantix has been a nightmare! I started experiencing severe anxiety, insomnia, and mild sadness after ramping up to the full dosage. When I discontinued the drug for these very reasons, it seemed like my whole life imploded! I was extrememly depressed, not suicidal but I felt like I had no future and had failed everybody in my life. I would pace the floors of my house for hours and couldn't stop, no matter what I tried to do-- a living hell! Fortunately the severe depression has tapered off, but I'm still unusually emotional and suffer from panic attacks fairly frequently (at first about an 8 on a scale of 1-10, now thankfully they're somewhere between 4-6 on the same scale). I'm also sleeping poorly, but am able to rest much better now than before I quit taking the drug. I've never taken street drugs, but I imagine this is what a "bad trip" must be like... and it's lasted about 2 weeks now! I wouldn't give this stuff to a dog, no matter how many packs a day it smoked!!! Be careful and make sure you discuss side effects with your doctor.
Posted by: Jeffzilla 7/5/2007 8:58:37 AM

I posted the above comment last week... wanted to give a follow-up to share a ray of hope for anybody else who might have been going through what I experienced. Three weeks after discontinuing Chantix, I'm still a little moody but no longer experiencing the wild swings from one extreme to the other. My moods are no longer so intense that I get carried away with them-- I can at least rationalize that these feelings aren't real, that they're the effect of a drug and nothing more. Also, the panic attacks that I was experiencing are really more like occasional periods of extreme stress now. I don't feel like myself yet, but I don't feel like a total stranger either!!! The discomfort that I'm feeling has gone from being a nightmare (the week that I quit taking Chantix) to an unmanageable mess (last week) to an mild annoyance (this week). If I had to guess, based upon the progress that I've made so far, I'd say that six weeks out I should be "back to normal" again. Good luck to nybody out there who is wrestling with the hell that I went through-- I know there probably doesn't seem to be any hope or any future right now, but YOU ARE NOT ALONE!!!
Posted by: 7/10/2007 9:43:36 AM

took it for a month and stopped after falling into deep depression and suicide attempt.
Posted by: Linda 7/10/2007 9:37:52 AM

I posted a comment om June 25. Wanted to follow up to it. My husband is physically fine after his experience, however, he is still having issues with remembering things. He is fatigued still and really has lost a lot of his drive. I just want to stress to anyone wanting to take this drug to PLEASE talk over all the side affects with your doctor. We were totally blindsided by our experience and want people that are considering taking this drug to be aware of ALL the possible side affects. I also saw that they are saying this drug may be a new drug to help fight addictions such as acolholism. If it is going to be used for a broader purpose, I hope that Pfizer will warn people more. If you have had extreme side affects you should contact Pfizer directly. They have a number listed on their website to report problems. And again, please report to the FDA. They have a form you can fill out online and submit online too. One more thing....for people that are having success at stopping smoking....research shows that 78% of people that quit, will either be using some form of nicotine replacement or go back to smoking within a year of stopping Chantix. With numbers like that it doesn't seem to be such a wonder drug. And definaltey not worth the risk of the extreme, yet rare (as Pfizer states) side effects.
Posted by: Deanna 7/10/2007 9:36:53 AM

Well, it sucks that most of the folks here have had issues with the Chantix. At least I know I'm not alone. The first 7 days of build-up went somewhat okay, but I never quite liked how it made me feel and I was aware that my urges to smoke were not reduced. Today was Day 8, the "QUIT DAY" and the day when the dosage doubled for the 2nd time in the build-up cycle. Urge to smoke, from morning until early this evening, was not lower and I felt like crap; I now know that I had a moderate anxiety attack all day at work. Really wasn't expecting anxiety; I was waiting for the nausea that never came. The sum total of my Chantix experience thus far is that it has NOT reduced my desire to smoke (to dose with nicotine) , but it has given me the bonus of feeling awful, mentally and physically. Pharmacist told me that I can just stop taking it; weaning off is not necessary.
Posted by: Jerry 7/11/2007 8:09:14 AM

Reading through all the postings I can see that I have experienced much of what everyone else has using this product. My only concern is the long-term effects. I hate to find out that this causes some sort of cancer. I still smoke 2 to 3 cigarettes a day but this is the result of smoking 2 packs a day for 25 years. I'm doing well in my own way of quitting. I experience nausea each and every time I take the pill; some time's worse than others do but it goes away within 10 minutes. I have learned that if I eat something, wait about 15 minutes, and then take the pill with a glass of water the nausea experience is dulled. I to have to admit that I have been moody and short tempered since I started on this medication, but it is less severe than being on Welbutrin XL. Welbutrin, though an anti-depressant caused me to become really depressed and moody. One time, after being on the pill for 1.5 months I got really depressed about an old friend that lives in another state. I had not thought about that friend for over 15 years and "just like that" I felt as if they just died. I will gladly put up with the nausea to quit smoking. I will even put up with the mood swings for a couple months. I have to quit but my will power is very poor. I feel much better even cutting down the amount of cigarettes each day. My weakness is the smell (believe it or not) of a burning cigarette (not the smell of someone smoking all day) and sometimes how it calms me down. This method has been the best one so far that I have tried and I will stay with it even though my medical insurance does not cover the costs.
Posted by: Brian P 7/30/2007 10:16:38 AM

I was on Chantix for a month. Two pills a day was too much, went down to one pill a day, and then to a 1/2. Was still not feeling right so I stopped. I thought I was totally losing my mind. Had high anxiety, forgetful, basically going nuts. I called my doctor and he said that's a normal side affect. It's been a week now, feeling almost back to normal. But I am smoking again...only have about 4 day as opposed to the pack a day I used to have before taking Chantix. But just want everyone to know that while Chantix helps you quit, when you get off it...it will make you crazy for a while and will have you crave cigarettes again as well.
Posted by: Carol P 8/19/2007 8:14:42 AM

my husband took chantex and fell asleep and had a hard time with staying awake he was taking lexapro so we had him stop lexapro till he stops smoking he hasnt quit the start date was 7/16/07 does any one have any ideas
Posted by: melody c 8/21/2007 6:21:50 AM

I'm into my second month on Chantix. The good news: I really have lost my desire to smoke. But, it's been at a cost. I can deal with the mild nausea, the headaches and the sleeplessness. However, I've completely lost my sex drive, am mildly depressed and I'm irritable to the point where I find myself flipping out at my coworkers (not good!). I plan on sticking with Chantix through this second month and then reevaluating if I can stay quit on my own.
Posted by: Anna 8/24/2007 9:52:34 AM

I am really nervous. My sister has been on Chantix for about one month. She has been taking lexapro for years for depression. Since the chantix she has been extremely moody, getting upset quickly at stupid things and doing a lot of yelling she also seems to get annoyed very quickly. I've been online trying to find out what is wrong with her. I don't want to tell her that I think it is the Chantix because she has not been smoking for a month and I am proud of her. I am nervous though that she may end up having some sort of breakdown. She definately is not herself.
URL: http
Posted by: Jul 8/25/2007 6:40:57 AM

I know several people that have taked Chantix and, after they quit, they blote up like they are pregnant! Some say it goes away after awhile but my wife still is bloting! She is a vegetarian and eats only small meals a day so we know it isn't diet. Are the people I know the only ones ar are there more of you out there. I agree that FDA allows too mnay medications release prior to complete investigation.
Posted by: Doc 8/26/2007 4:48:42 AM

I was on this stupid drug for four months. I lost all desire to do anything, and thought about suicide.I had controlled my type two diabetes for ten years with diet alone, and had no blood pressure issues. All of that changed with the Chantix. Now I am looking to have to take insulin for my diabetes and my blood pressure is way up. My sister never had issues with her blood pressure until she used Chantix. My advice is to forget using Chantix. Better off smoking and enjoying what you can of life than to want to kill yourself.The government has the perfect cure for smoking and that is to make cigs illegal, but they don't want to lose the tax money.
Posted by: Gail 8/30/2007 2:16:16 AM

worst depression ever - how does one get off this drug?
Posted by: Michael 9/10/2007 5:26:52 AM

I am so thankful I found this website with all the information on Chantix. I have been on this drug for 2 1/2 mos. and thought I was going crazy. I have been extremely depressed with horrible thoughts of suicide. Was working out at the gym yesterday and all of a sudden I had thoughts of buying a gun and shooting myself. I know this sounds nuts. Someone tapped me on the shoulder to say hi - that's what brought me back to reality. This is like a twilight zone I go to whenever I get this suicidal crap in my head. That's what's so scary - what if I someday I don't come out of that zone. I have always been a stable person with only some depression experience after my fiance died unexpectedly 2 yrs.ago at age 52. Now this depression haunts me daily. I also have bouts of crying. I thought I was going crazy until I read the posts. Severe anger has also been a problem. I also have the most horrible taste in my mouth which never goes away. I was a 1-1/2 to 2 paks a day smoker for 30 years. I still smoke 2 cigs a day - can't quit totally. I'm afraid to stop taking Chantix thinking I will start again and especially since I read how depression is worse after you quit the drug. Also had a panic attack that was so bad it terrified me. My friends also are saying that I have changed - am not the same person anymore.It's a wonder I have kept my job which is high end and high stress. My ability to concentrate is at an all time low. I think I need to see my doctor - this is scary.Can you safely cut the dosage down and not experience side effects?
Posted by: Sandy 9/10/2007 5:34:59 AM

I am happy to find out that I'm not the only one feeling extremely depressed after taking Chantix. Suicide has crossed my mind a few too many times and this is making me a little scared.
Posted by: Kim 9/11/2007 2:01:47 AM

I've only been on it for 3 weeks. Just started to notice a change in personality a couple of days ago. Tired, no desire to do anything, cranky and depressed. To those of you who have stopped for a while now, does it ever go away? If I stop taking Chantix TODAY, will it be better or worse? What about weaning?
Posted by: Sue 9/13/2007 11:17:10 AM

for the past few days, all i can do is cry. i feel worthless and actually looked around my wonderful remodeled house and thought about my great job and all i wanted to do was just die... somehow... at my own hand. i nearly had a panic attack because i could not get ahold of someone to talk to to help me through this. they were all busy, but i felt like they had died and left me all alone. i knew this wasn't normally me, so i just sat down infront of the computer and googled "chantix" and "depression" and came upon this site. it's a relief to know other people feel the same way. i also get the extreme nausea and insomnia- which are listed on the packaging. i also got a prescription for my husband which he has yet to pick up because he doesn't believe in medicine that alters your brain chemistry... i realize that maybe he's right. the scary thing is i just realized this and haven't stopped the med and am now scared to. should i wean or just stop?
Posted by: Anjelle 9/18/2007 10:17:29 AM

Did anyone see the Good Morning America broadcast about the man on Chantix and he had a psychotic break and his neighbor shot and killed him? I missed it and can't seem to find out any info on it. Also, if you are experiencing horrible side effects....tell your doctor. That is the ONLY WAY that the medical professionals will know that there are some bad things going on with this drug. After my husbands experieince in June (I posted his story on June 25), and seeing all these other people having problems, I think that this drug needs to be pulled, but the doctors think that it is a fix all. If they are told enough times that there are serious side effects happening, maybe they will start to take notice.How many people have already died and it has not been attributed to this drug? TELL YOUR DOCTOR IF YOU ARE HAVING PROBLEMS!!!!!ANd file a form with the FDA....you can go to their website and post when you have an adverse reaction to something.
Posted by: Deanna 9/19/2007 10:04:56 AM

You can see it at Good Morning America's website - there is a video there. The one who was shot was taking the drug - not the one who shot him so what does that say? The guy was acting weird and went over to his neighbors and the neighbor shot him? So what was the neighbor taking?? The death is attributed right away to the drug in the headlines - like the guy who was taking the Chantix went off the deep end and killed someone - it's only after you read the article that you realize that it was the neighbor who shot HIM!! What about the guy who shot him? What kind of a wing nut was he??I would like to say I feel bad for everyone who has posted here and hope you can make the choice for yourself and not based on everyone else's opinion - including mine - I am not saying what I am saying is the right thing - I only know how this worked for me.I would like to interject that my husband, myself and my son all quit smoking taking Chantix and I will be forever grateful for this drug. They say that smoking is like quitting heroin so has anyone considered that the so- called side affects of this drug may actually just be the affects of withdrawl from another drug? The nicotine? Doc's will put on an antidepressant like Welbutrin when you quit to help ease the anxiety so that should make it obvious that we do get anxious when we quit or why would they do that? We also took it a bit different than maybe most ppl. After 2 weeks of taking it the way it is prescribed we started taking it just once a day and then after a week dropped down to one every other day. At first we did this on the advise of our doctor because he said it would save us $ and then we realized that half the dose was working just as well. We would get a stomach ache for about 10 mins. at times but we knew it would pass and eating did help. I did have one panic attack that lasted about 2 mins. but I still think at least for me that the drug is the lesser of 2 evils. I am a 50 year old female who smoked 2 packs since the age of 14!!! I would not hesitate to take this again and suffer the side affects for a while - to me and my husband it was worth it but everyone needs to do what they need to do - just keep in mind that maybe some of what you are experiencing has to do with the nic. and habit withdrawl.
Posted by: Kathy 9/19/2007 11:20:13 AM

ok, i am so freaked out. i have been such a complete mess at work and very 'un-characteristicly' depressed. i actually have been bad enough to where i fear for my job and being a single mom, that scares me. i can get down at times but who can't? i have been on chantix for 5 weeks... but it's my 3rd time trying. the first 2 i made it for 6 weeks. i cut back but never did quit. i have been so down i decided today to go off chantix. now i am seeing the effects can go for weeks afterward? i am calling my doc tomorrow. but if anyone has a clue to how long afterward it lasts, please let me know.
Posted by: scoops 9/20/2007 10:57:33 AM

Just curious if any of you have stayed off smoking since stopping the Chantix. I am on day 13 of Chantix and still smoking but down to 4-5 cigaretts compared to the 1-2 packs per day I was smoking. I really have lost the desire to smoke it seems like more of a habit at this point. But luckily haven't had any mood issues that are referred to above, Ironically I am "clinically" labeled as bipolar so I would have expected from reading this that I would somehow be affected emotionally. But I haven't. What I have had is nausea, so I have been eating alot to cover that and inturn becoming very bloated, I have been craving all types of crap but nicotine is not one of them.
Posted by: Jessica 9/24/2007 12:14:13 PM

After 20 days on Chantix, I had stopped smoking for 9 days but I didn't feel "right." I was depressed, had lost the desire to work, had muscle aches, and couldn't concentrate or focus. I decided to quit Chantix. I had no physical effects from quitting, but mentally I wasn't back to normal for 7 days. I am convinced there is something seriously wrong with this drug that Pfizer has not adequately disclosed.
Posted by: Roger 9/29/2007 12:06:58 PM

JESSICA: I'm on day 15 on Chantix and am still smoking approx. 3-5 butts a day...like you, i am way down from the two packs daily I did prior to the medication...I am getting some muscle aches, bur rarely have gotten nausea AND I'm taking the Chantix on an empty stomach in the morning...??...I did however, eat breakfast one morning, THEN took the pill and had ZERO side effects...obviously thats probably the cure-all..AT this point, I would be VERY glad if the Chantix "allowed" me 5 cigarettes a day...just enough to take the edge off..
Posted by: steve 10/2/2007 12:29:25 PM

Chantix makes me feel like sh!t. I have GI problems (nausea and heartburn), sleep anxiety, tired as hell and am feeling depressed and anxious. I take it with food every day so that doesn't help my side effects. I feel like this is going to kill me quicker than ciggies.
Posted by: Matt 10/5/2007 11:25:03 AM

See Karen's bog of June 14th. She notified the FDA but I am affraid it was too late. Karen in no longer with us.
Posted by: Janice 10/6/2007 9:35:29 AM

Janice,What happened?!?! I myself being one of the people who experienced the suicidal thoughts (I posted above), your post sent shivers down my spine, and brought tears to my eyes. Do you mind if I ask?
Posted by: Brenda 10/7/2007 12:39:38 PM

I took the lowest beginning dosage of Chantix and felt like a great distance was occuring between me and my addiction and need for cigarettes. A few days after going to the second increased dosage, I developed severe and profuse nosebleeds. (I had neve had a nosebleed in my life before.) As soon as I stopped the Chantix, the nosebleeds stopped. Now I'm still smoking with COPD. Has anyone else had the nosebleed reaction. So many of my friends and relatives have quite with Chantix and say it's a miracle!
Posted by: Jane 10/13/2007 5:43:01 AM

I have attempted to post a message many times it does not get posted. My husband was on Chantix for 2 months. His personality changed dramatically, he committed suicide on the night of 4-23-2007. He had been drinking. Do not drink if you take this drug!!!!!
URL: srtggt
Posted by: Shirley Taylor 10/14/2007 9:28:16 AM

I am a 36 YO bipolar sufferer and today would be my day 10 on Chantix, but I simply could NOT do it. Instead, I had to get online and search to see if this medication affected bipolar patients because for the past 2 days, I've been having VERY strong suicidal thoughts. Imagine my surprise when I stumbled across this site and discovered I am not alone. While searching the web, I had also discovered that Chantix excluded a select group of individuals for thier study, one such group being those with bipolar disorder. One thing is for certain...this medication did curb my desire for a cigarette, only because it replaced those urges with negative and suicidal thoughts. I'm done with this medication and I sincerely hope sites like this will help to prevent others from making a potentially fatal mistake by taking this medication.
Posted by: Heidi Mutcher 10/22/2007 12:07:33 PM

I took Chantix for only 4 days (i.e. only four 0.5 mg pills in four days). I'm fortunate in that I've never had a problem with clinical depression (normal depression at times, yes) nor am I bipolar (which I understand is quite debilitating). But the third day into the Chantix program, I started get extremely agitated and could not concentrate. And, the fourth day I experienced the most acute anxiety I have ever felt in my life. Positively terrifying. I'm a 48 year old man and I felt I was on verge of crying for most of the day - and for no reason.So I didn't take the second dose that day, nor have I since. But the next day was just as bad. I know this sounds melodramatic, but I felt like I had to get out of my body and I couldn't. So I drank myself silly, which is probably the worst thing you can do.Today, two days later, I still feel like crap but I'm feeling a bit more sane. So I googled "anxiety Chantix" and found this site and read every entry. It made me feel so much better to read all of your input, though some of it was quite disturbing and tragic.I know a woman for whom Chantix has been a blessing, so I won't condemn it. But still I think that anyone who has had a negative reaction to the drug should report it to the FDA or Pfizer as soon as possible. The on-line FDA form for reporting drug reactions was kind of difficult to find and it's annoying to fill out because of continuous popups. This link should get you there: (https://www.accessdata.fda.gov/scripts/medwatch/medwatch-online.htm)Thanks and good luck to all,
Posted by: kris 10/22/2007 6:57:39 AM

Has anyone had problems when they lay down that they almost stop breathing? I just took my second pill about two hours ago and I kept jurking myself awake like I couldn't breath! I do have anxity issues however I haven't had any problem with them for a couple of years. I got out of bed and made myself vomit hoping the pill or what was left of it would come out!! The first three days on it I couldn't stop yawning and felt sooo tired. I'm not so sure I am going to take this anymore.
Posted by: jodee 10/25/2007 2:27:26 AM

What happened to Karen? Was it because of Chantix? Did anyone see the article in People magazine last week? The FDA was quoted as saying they don't really know all the side effects of this drug, and they have to wait and see how people react as more people take it!! It is like they are using the general population to try out this new wonder drug....I really think that they think as long as the number of people who quit is at 45% then it is okay if a few people are depressed or worse. If the government is not watching out for us....who is? Pfizer only worries about the profit margin!!!
Posted by: Deanna 10/26/2007 8:49:39 AM

My Chantix experience has been AWFUL.I first took it last year and had episodes of major panic,anxiety,depression and they were intensified whenever I drank alcohol.Awful dreams of someone taking advantage of me,me wandering off some where/with someone,waking up crying and they are so REAL.I quit taking it because I couldn't handle the nausea.I thought that was the only side effect from this.So I was told.I had tried this drug off and on from Sept.2006-Sept 2007.Each attempt I could never handle the nausea so,I always gave it a break,then tried it again.My mind has really been "slipping",I'm an emotional wreck.I "attempted" suicide in June this year,it crosses my mind every day still.My depression/anxiety seems like it's in overdrive.Last week I tried a detox for 7 days to see if that would help and I started to feel somewhat better....I had a few beers and the nightmare started all over again.I dreampt"I hope",that I was down the street at someone's house and a white truck brought me home.My dreams are always of me leaving the house and wandering off.Shouldn't this crap be out of me by now?I blackout all the time now.I hate even leaving my house because I feel like I'm pissed off at the world.Yesterday I kicked in (and broke)our stereo and through a phone at the wall.I couldn't tell you why,I just got mad and shaky.Back in August,I had one of these dreams that I was banging on our neighbor's windows and woke up shaking like h*ll and crying.Completely confused.The doc tried to admit me and said that I needed about a week of in-patient treatment.They locked me up all day like I was a criminal.All I asked for was some help.This crap really needs to be taken off the market and I rather smoke than to go through this crap.All I want is my life back.
Posted by: Christina 10/29/2007 7:22:49 AM

I started Chantex in August 2007 and stopped after 10-days of using it because of not being able to sleep and constipation. I have stopped smoling but now continue to have problems with constipation, I've been to my Doctor on 4-occassion and at the present time has been referred to Doctor (Gastrologist) in Moore County. I've gone fron 120 pounds to 139 pounds even though I'm not eating more than normal. After eating I begin to swell immediatly my bowel is now the size of my pinky finger and about 3 inches long (I'm not a Doctor but I know my body and I know this is not normal). I wish I had really tried to stop smoking on my own.Posted by Lugennia Hunt
Posted by: Lugennia Hunt 11/9/2007 1:40:59 AM

ok, now how do I get the anxiety to stop? I haven't smoked in 63 days ans I've been off Chantix for about 40 days. Will the anxiety go away?Mikw
Posted by: mikro219 11/16/2007 12:27:22 PM

My condolences go out to you Shirley who lost your husband.I notice that many who have taken Chantix are also taking medication for anxiety. I come from a background where we swallowed our personal issues...we toughened up...and did not talk about them (even with the medical community). I'm pretty much high strung about half the hours in my life....this includes the hours while I'm asleep. I took Chantix and miraciously...magically felt no desire to smoke. The only side affect I can attest to is that my dreams were enhanced. Just tonight while watching the CBS evening news Katie Couric breifly touched on the topic of Chantix use being associated with suicidal feelings.
Posted by: robert 11/20/2007 6:16:04 AM

We live in Nebraska and in the Lincoln Journal Star, there was a comment in the national section that the FDA is now investigating whether Chantix is linked to suicidal thoughts and violent behaviour. Those of us that have had problems with this drug, need to report it to the FDA so that they now what is going on. Please, don't wait. REPORT it if you have a problem. I did when my husband had problems. (I am posted on this sight in June.)
Posted by: Deanna 11/23/2007 10:14:19 AM

My son, age 25, died November 10 of this year. He was an alcoholic and a drug addict, and had started taking Chantix in October, hoping to stop smoking before the birth of a son expected in January, and because he had heard it would help stop cravings for drugs other than nicotine. For the last 3 or 4 days of his life, he was unable to sleep, and when he would fall asleep would wake up having dreams that he was killing himself.I know he had other drugs in his system, and I know his actions indicated drug use again, but I now wonder if the Chantix had anything to do with the dreams about dying and killing himself. And the sad thing is, I may never know.
Posted by: Connie 11/23/2007 7:39:25 AM

I’ve been taking chantix for a few months and I’ve suffered nausea and a little numbness in my leg but that’s it. I still cheat a little but it really doesn’t do anything for me. I think what most people forget is that the drug is a nicotine blocker. As soon as you take the first pill you will start developing nicotine withdrawal. We all know what those symptoms are right? Irritability, frustration, anger or anxiety, difficulty in concentrating, restlessness, increased appetite, problems falling asleep or frequent waking, slight depression or feeling down. I’m no longer an addict and the symptoms get less severe as time passes. The drug is doing what it was designed to do. I’ve cut back to 1mg a day now b/c I want to be on it longer and feel that the second pill gives me no added benefit after testing it a few times and on the lower dose the numbness is lessened. Anyhow take care all and keep on quitting.
Posted by: Bobby 11/26/2007 1:51:37 AM

I took Chantix for about a month. Almost immediately I became despondent, fatigued, lost interest in everything, and I guess just overall depressed. I was in a fog most of the time and I didn't have ANY motivation at all. I couldn't even form complete sentences and avoided people in general. It just wasn't me and I never linked Chantix with these symptoms. I stopped about 3 weeks ago and just now am returning to feeling normal. Yes, I had the dreams (but they weren't all bad!) but thoughts of dying were in my head the whole time -- I never attempted suicide but had thoughts of just giving up and wouldn't have minded just passing on. Quitting smoking is hard enough - I've tried EVERYTHING but I seriously doubt I will ever try Chantix again - I became a very weepy, sad, and lost soul on this drug.
Posted by: Sharon 11/26/2007 4:37:43 AM

I started taking Chantix October 2006 and quit on the 3rd day of the first week. I had smoked for over 50 years, tried all the other quit smoking methods and nothing worked, and I was a chain smoker - 2 packs a day. I never, never experienced any side effects and started skipping every other day of taking the Chantix. Within a month, I no longer had the desire to smokw and quit taking chantix. That was over 13 months ago, and I have no desire or thoughts of ever smoking again. Chantix was definitely my "miracle" drug.
URL: Roadrunner
Posted by: Mora 11/26/2007 9:35:01 AM

I took Chantix for approximately 3 months. I have been taking Lexapro for depression for a couple years and am diabetic. My problems included the enhanced dreams. I dreamt a truck was dumping rocks on me and when I rolled over to avoid the rocks, I actually rolled out of bed. I didn't read about anyone having a problem that I have experienced. Now that I am off Chantix, I have awakened to a major financial problem. While taking Chantix, I skipped payments and gambled and shopped. The gambling would get me away from the fact that my house was a disaster and I didn't want to be there. Now, I have been able to get my house work under control since stopping Chantix but am not sure what to do about not being able to pay my bills and all my credit cards are maxed out and I have no savings nor any way to pay all these bills. I, also, have some health problems now that I had been taking care of but began ignorning when taking Chantix. Is there anything that can be done or some help somewhere now?
Posted by: Linda 12/6/2007 10:46:26 AM

I started CHantix in october of 07. By November I was out of control: depressed,suicidal. I was saved by a co-worker who found me while I was trying to do the task. I have a 35 year smoking history and have quit twice: once with gum and once with the patch. During these previous attempts to quit smoking, I had none of the side effects I have had with Chantix.I take no prescription meds and have no history of mental Illness. Buyer beware!!!!!
Posted by: bpd123 12/8/2007 8:03:00 AM

I watched, helplessly and in HORROR as this drug destroyed someone I love. My sister switched careers, dumped friendships, burnt bridges, became depressed, and became increasingly paranoid as this “miracle” drug stopped her from smoking. Yes, it did help her to quit, but, at the same time it changed her personality and life. She is no longer a happy person, so, I’m not sure she is healthier by being a non-smoker. She was also worried about smoking causing wrinkles….really, now! Her happiness was much more important than wrinkles!! She has been off of Chantrix for aprox. 3 weeks and she is STILL not back to herself. After reading some of these posts I’ve concluded….#1. I’m happy she is still alive. (Such heart wrenching stories)#2. I don’t know if she will ever be back to “normal and happy” or content.#3. I’m VERY worried about long term and possibly permanent effects Chantrix may have had on her nervous system, neuro-transmitters (sp) and brain function!May peace and HOPE be with you all during this Holiday Season.
Posted by: Jennifer 12/8/2007 11:06:46 AM

I started taking champix 3 weeks ago. At first it worked well, I didn’t feel the urge to smoke; I still missed smoking but just didn’t need the nicotine anymore. My personality was the same as before but I started to get depressing thoughts from time to time, id be sitting watching TV like usual but then I would get a small wave of depression, but it was nothing major so ignored it. When I entered the second week of treatment and increased my dosage to 1mg tablets things started to change. I felt unmotivated and generally down. After two days on the 1mg tabs I lost the plot. I was constantly crying, and thinking of suicide. I have never suffered from depression before this moment. I've found myself obsessing about an ex girlfriend I broke up with months ago. I hadn’t thought about her at all since we broke up, until the second week of champix. I have not been able to curb the thoughts, my anxiety is through the roof and I can’t function. I have been to my doctors and told him about my suicidal thoughts and he has told me to stop talking champix. I stopped on Tuesday, today is Thursday and I still can’t shake this feeling of depression. It’s as thought my mind is depressed and it is looking for reasons to explain the depression (hence thoughts of my ex girlfriend) I've read all the above posts and it has helped me a lot. However it seems to vary how long it takes to get back to normal, with some people saying they haven’t got back to normal after months. Is there anyone out there that has suffered what im suffering and have come out the other end as a normal person? If so how long did it take?
Posted by: Jason 12/13/2007 8:31:22 AM

Everyone should be concerned about this drug whether you are a cheerleader or suffer from side effects.Why? Pfizer used a very small sample( less that 4000) of all "healthy smokers". Anyone with health problems were excluded. Over 4 million prescription have been written for chantix. Most estimates I see say that 1% or less will have the rare/infrequent side effects. At 1 %, that means there are 40,000 of us. If you search the web sites and blogs(including the medical blogs) you find reports of depression, suicide, disorientation, passing out, aggression, anger suicidal ideation, etc.... These individuals are a danger to themselves and others. Imagine someone driving and passing out or becoming disorientated. the result could be deadly.
Posted by: bpd123 12/13/2007 9:18:47 AM

I took Chantix two weeks as prescribed, … third week I cut the pills in half, … then I stopped completely. The depression still continues now a week after stopped taking it.. … actually it seems it is even worst. I cannot control myself, I get in the car, close up the windows and scream till my larynges come out, then I start hurting myself. It is horrible … I am constantly crying, and thinking of suicide. Next week I’ll go to my doctor and ask for help. I don’t want to loose my job, my relationship and start destroying things and myself.
Posted by: C..V.. 12/15/2007 1:53:02 AM

Hello, I've been on Chantix for 3 weeks and it has definitely taken the edge off of quitting smoking. I actually have less anxiety than I normally would. I think this is because chantix is very chemically similar to an anti-depressent which would also explain why mao inhibitors like prozac have the same warnings of suicide ideation ect. I would be intersted to see if some of these depression and anxiety cases could actually be due to nicotene withdrawls. I definitely would need zanax and zoloft to help me with that if it weren't for chantix. Oh, and if you do use the patch, do not go to sleep take it off like 2 hours before you go to sleep or you will have the worst nightmares you have ver encountered! Damn it, why did we start smoking in the 1st place!!!
Posted by: BE 12/19/2007 11:24:51 AM

I am bipolar and this will be day 5 on chantix. This will also be my last day for the drug. After day three, I woke up with terrible depression and lack of desire to do anything. I am fortunate to say I haven't had a major depressive episode in well over a year. I first thought my bipolar medications were no longer working until I stumbled across this site. I am relieved to atleast know the source of my depression is not from being bipolar.
Posted by: Steve 12/19/2007 5:24:07 AM

Hello, I’m a healthy 39 year old. I took Chantix for about 3 weeks and what an awful experience I had with it. I have friends that have taken it and have had no side effects at all and stopped smoking completely. I take no other kind of medication and have no mental problems or aggression problems. I do have a nightly “toddy” to help me sleep. I started having bizarre dreams after I took the 2nd pill. The bizarre dreams accelerated to homicidal dreams that were VERY graphic. After I started taking the blue pills, I would have severe fits of rage that would last several hours. I would feel agitated all day. I never felt suicidal. I also had a lot of stomach problems with it – gas/bloating. After the last fit I threw on my family, I decided to stop taking the pills cause I was afraid I would kill someone. Thankfully, my dreams and agitation stopped a couple of days after I stopped taking Chantix. I still smoke but not as much as I did before I took the Chantix. I am trying to wean myself off of the cigarettes instead of taking brain altering drugs to take the cravings away.
Posted by: Amy 12/28/2007 5:47:26 AM

Today is my 4th day on the drug and I'm not going to take it anymore. Yesterday I was depressed and its here today too. I have a history of depression and my doctor DID warn me that depression was a side effect. I called the drug info hotline and its not mentioned there. I'll be honest, I'd rather smoke till the day I die than go that mental health hell again. Please be careful.
Posted by: Susan 1/1/2008 4:24:23 AM

I took Chantix for 9 days and then had to stop. I had a few side effects during the first week such as, trouble sleeping (I would wake up every night @ 2am), upset stomach (even though I took the pill with food).However, the first week was nothing compared to what was about to happen. During the first day of the second week the depression started and it was nothing like nicotine withdrawl symptoms. I had crazy dream on the first night of the second week. On the 2nd day of the 2nd week I was fine when I woke up, but then I ate breakfast and took the pill and the depression started creeping in. The depression got so bad that I briefly thought about jumping out of a car while it was going 65 mph. Luckily I didn't and I realized that this medicine is very dangerous. As the day went on I started to feel a little better because the stuff was wearing off. I quit taking Chantix on that Sunday and have felt happy again. I also haven't smoked since Saturday (4 days ago).
Posted by: JP 1/2/2008 1:24:50 AM

I took Chantix for a few weeks. I think I made it 5 days without smoking. I can't remember what made me stop taking the drug... But I stopped months ago and am finally starting to feel like myself. Shortly after quiting Chantix I became severely depressed. It was the worst! I spent a couple of months crying on a daily basis with no realy explanation. I felt like my social skills ran away, and I did not know who I was. I have never been this way before in my life. I have considered trying it again, but after reading everyone else's experiences, I just can't.My mother is taking the drug right now and it is working well. She has gone 5 weeks without a smoke. I am proud of her, but am worried about depression catching her too.
Posted by: Starr Harris 1/2/2008 4:06:49 AM

I started taking Chantix a month ago (early Dec) and was able to reduce to a couple of cigs a day, and quit by the 3rd week. I had some family drama, and smoked a whole pack the day after Christmas, but haven't touched them since. (I recommend that you don't allow yourself to BUY cigarettes...if you have them, you'll smoke them, even if you don't care to). Also, I recommend Ambien to help you sleep--that might get you through some of the crazy dreams. Anyway, while on the Chantix, I experienced the normal side effects, depression, bloating, nausea, lack of interest in anything, sleeping a lot...so I stopped taking it. Three days later, I had a couple of martinis and blacked out. According to my boyfriend, I had a 4 hour psychotic, screaming, crying episode where I beat my head and face on the ground and walls, and yelled things that would never come out of my mouth. Then I vomitted and passed out. Other than a concussion, some major bruises, cuts, scrapes, and gash across my face, I'm ok. I have had a few slumps in the week after stopping the Chantix where I have anxiety attacks and cry uncontrollable for a couple of hours, but I am starting to see the end of the episodes. At least I understand they are from the Chantix withdrawal.I can say that I'm smoke free, and still a little depressed. Oh, and my boyfriend hasn't allowed me to drink since the episode (bless his heart).
Posted by: Jennifer 1/3/2008 11:13:57 AM

I am so thankful I found this. I thought it was just me. I was on Chantix for three months. The entire time, I felt in a "funk". Not my normal happy go lucky, laid back self. I gradually lost interest in not only cigarettes but everything that I once enjoyed. I withdrew from friends, no longer found satisfaction from work, didn't care that the house was dirty, etc. I have been off Chantix for a couple of weeks now (still smoke free and doing well there) but I am falling into a deeper and deeper depression, crying jags for no reason, anxiety attacks -- I thought I was going crazy and having a nervous breakdown! I just started taking some antidepressants two days ago. I seriously hope they have an effect soon.
Posted by: Marie 1/5/2008 4:05:26 AM

I have been taking Chantex for approximately 4 1/2 months. I have experienced the side effects that are mentioned by the manufacturer but I also suffered from terrible side effects if I missed doses. I tried to gradually stop taking it but became very anxious and aggitated. I slowly over the four months become more and more depressed until one day hit bottom and started having suicidal thoughts and became violent and felt like I had suffered from a nervous breakdown. I take Cymbalta and Lamictal already for bi-polar and at first the Chantex helped- I was able to quit smoking but then I realized I was addicted to the Chantex. I was surprised to learn that others have experienced the same. These side effects have life changing circumstances and need to carefully considered by doctors and patients before people lose ther lives or everything that means something to them in life.
Posted by: Kristi 1/9/2008 1:38:35 AM

Hello,Has anyone who has experienced awful side effects (depression, anxiety, suicidal thoughts) found a successful way to treat the side effects? What about success treatingthe residual effects? How long have residual effects of depression etc. lasted? Has anyone had a Dr. confirm any of our beliefs that chantrix is causing the depression etc? Withdrawal from nicotine may be horrible but, it DOES NOT last as long as the suffering mentioned in many of the above posts. The explaining away horrifying side effects that people are complaining about in these posts by calling it nicotine withdrawal seems to be a big sham. It seems to me there is a “blind eye” being turned to everyone’s concerns about side effects. I know the FDA is studying this drug again. And, to that I say, PULL CHANTRIX OFF THE SHELF until these claims are acknowledged and studied. How many people does it take to suffer tragedy before there is action? How long can the adverse side effects last?My sister is suffering greatly after being off chantix for solid 2-months now. Her depression continues, suicidal thought are present, nightmares are frequent, paranoia is constant, and she has a hard time leaving the house. She has been unable to maintain a job and she has gone through several in the past 5-6 months. She has stopped smoking (a nonexistent triumph at this juncture) yet she has also lost all quality in her life. Smoking seems to be a much better choice when compared to the life altering side effects that are prevalent with this drug.She is under psychiatric care and medicated. I feel like she is being treated for something that is still not fully understood. So, I am left to ponder the question…..Does anyone really know how to treat and conquer the chaos that chantix has left her psychological state in? I hope help is on the way for every person who is in need of answers!
Posted by: Jennifer 1/10/2008 11:46:34 AM

The spelling in my last post was wrong- Chantix is the correct spelling and that mis-spelling should not be confused with any other drug.
Posted by: Jennifer 1/10/2008 11:09:41 AM

I can recommend to anyone -DO NOT DO THIS DRUG. I had quit two times smoking before completely in the last 7 years. One time using smoking pot (which is a great way to get off and easier to stop smoking) and the other with the patch (which really works past 2 or 3 weeks). Instead of taking chantix buy some pot and a vap to save your lungs. Wean off the pot after 4 or 5 months. You won't want to kill yourself, might forget about smoking cigs completely and can get a good night sleep. You might have a little morning fog but wouldn't you rather just have another cup of coffee instead of sucidal thoughts and anxiety attacks.I have been on Chantix for 8 months. This stuff is complete crap. I used to do extascy all the time. Much better drug, makes you feel good, and has less side effects. I am weaning of this crap in the next week. The only advice I can give those who are hooked on this junk is to smoke cigs, then wean off with patchs and gum etc. Then just get off of it. Right now I am on 1/4 a chantix pill and 1/5 a 12mg nicotine patch. I really don't need either. Have not had a cig for 10 days. Don't buy that 3 months you need to be on it crap. All it take is changing your willpower and habits. Chantix makes it worse. I punched a hole in my office wall for no reason. Now i know. This stuff is not good. I almost cheated on my wife, and would hav paid sex with anyone, I slit my arms, almost got myself killed all because this stupid drug.Get off of it. Anyone can stop smoking its not easy. But this drug will make having a heart attack look like a hop through the park...
Posted by: Erikl 1/11/2008 9:27:04 AM

I took Chantix for 3 months and sucessfully quit smoking 8 months ago. I think that it's interesting that a poison such as nicotine and who knows what else is put in American cigarettes is ignored and Chantix is blamed. Why is no one talking about American cigarettes triggering the brain to release dopomine? and when the nicotine is no longer triggering the release of dopomine the individual is depressed?Some depressed people are obviously self medicating with nicotine. Cigarettes can probably produce depression following cessation due to the diminished release of dopomine. Why not ask the AMA why a poison that kills millions and disables millions is legal?
Posted by: Eddye 1/17/2008 9:00:59 AM

What can I say. The faces (or names in this case) may be different, but most of the stories are the same. I only took Chantix for several days, and not even consecutively, and it made me so sick that smoking was the last of my worries. I felt like I had the flu, my body and head ached, and on top of it I had a constant feeling that I would vomit any minute (which I never did). The dreams I had were lucid, strange, and at times terrifying. Like many of you, I soon began feeling anxious and depressed. This morning my fiance and I had an argument and he pointed out that I lately seemed unhappy, angry, and unmotivated. It was then that I confessed (in tears) that I had been depressed for a while and had actually considered taking pills or hanging myself on numerous occasions. Then, tonight as we were watching T.V., during intermission a commercial regarding Chantix, suicide, and a lawsuit came on. My fiance got on the computer and searched the topic. And, needless to say, I am shocked that with all this controversy going on there are doctors out there still prescribing Chantix to any and all who wants to quit smoking. As for the smoking, I have had several cigarettes since my initial quit date, but as I said before, the pain and misery I have and continue to experience due to taking Chantix is too much and I doubt seriously that I will go back to smoking 100 per cent.
Posted by: Grace 1/22/2008 12:48:01 PM

Oh my gosh! "Dr. Oz" gave Chantix a plug on the Oprah show today 1/22/2008. There was NO mention of Pfizers ne warning, the show may have been taped earlier than the warning's "upgrade" was posted.
Posted by: Jennifer 1/22/2008 6:04:41 AM

I have tried to post 2-times with no luck. Please forgive me if this posts more than once :(Today 1/22/2008 Dr. Oz gave Chantix a "plug" on the Oprah show. Maybe the show taped befor Pfizers "upgraded" warining for Chantix. However, there was NO mention of suicidal thought's being associated with the use of Chantix. WOW millions of viewers just saw that!
Posted by: Jennifer 1/22/2008 6:44:43 AM

I was a 40 year smoker now have copd,tried many things to quit smoking ,I sucessfully used the patch ,the highest mg for 3 mo and used the nicotrol Inhaler(my cheater cigarette)Im Happy to say no smokes for 3 years. I was in every non smoking clinic I could find,with no sucess,I tried this myself and it worked. And if you feel the urge for nicotine you can use your cheater anywhere,even in church & the plane. Good luck ,it really will work!
Posted by: Sandy 1/26/2008 10:47:22 AM

I started taking Chantix 7 days ago and the depression has been building since day 2. For the past two days I have been waking up thinking, "I am going to kill myself today." I feel completely out of control of my emotions, and it's just getting worse. My doctor just recommended that I stop taking it immediately. I am anxious all the time lately and have this real feeling that soemthing very, very bad is going to happen. I don't know what to do......
Posted by: Amy 2/14/2008 10:50:51 AM

Thank you all for telling about your experience with Chantix.I picked up my prescription a couple of days ago and got on here to sign up for the support group.I suffer from depression and panic attacks already and don't need to take anything that will make it worse so I will not be taking my pills tommorrow as planned.I am truly grateful to all of you for saving my life.
Posted by: Becky 2/18/2008 12:13:18 PM

On January 27th, I began taking Chantix and by February 10th, I began having sever anxiety, depression, suicidal thougts and nightmares. On February 12th I stopped taking Chantix and was perscribed Zoloft, to counter act the depression and anxiety. It has now been 1 week and 2 days since I quit taking Chantix and I am still suffering from depression, anxiety and just feeling plain crazy.
Posted by: Max 2/20/2008 2:55:12 AM

Thanks all for the Chantix experiences. They helped me rationalize what has been going on in my brain over the last few of months. Now it's my turn. I'll try to keep it brief:Mid Nov, 2007, 1 1/2 weeks into Chantix and I quit smoking. I felt great, lost weight and had the Libido of an 18yr old (I'm mid 40's).Mid Dec, 2007, I take only 1mg Chantix in the morning because I am only sleeping 2hrs/night.Christmas 2007, I stop taking Chantix because I am still not sleeping and cannot function very well at work or home.Mid Jan, wife makes me go to the doctor. Within 2 days my elation turns to bad anxiety. The doctor diagnoses "severe nicotine withdrawal" and puts me on the patch and prescribes sleeping pills (tamazapam 15mg). The next day seems better after having a 21mg patch - but I'm having cravings that I never had, so I decide to suffer and peel 1/2 patch one day, then the other half the next (10.5mg/day). Things seem OK but then I have mini-relapses; and I still cannot sleep. The weird taste on my tongue is driving me nuts... I travel for business across the country and someone offers me gum - wow, just getting rid of that weird tongue taste help ALOT. I smoke a cigar (no inhale) and take GABA from a health food store - the next day is hell. Several days pass and several trials and errors. I no longer drink coffee, take vitamins, take my prescribed sleeping pills, take melatonin or GABA from health food store. I would only drink bottled water and eat food - but have a few drinks in the evening to cope.I went back to the doctor: He wanted me to take Zoloft (antidepressant: another Pfizer drug). I refuse because I personally cannot tolerate antidepressants (they work opposite on me). I decide to fight it.Mid Feb: Finally - FINALLY, I feel like I'm starting to break free. I no longer have the anxiety, but I do feel weird and dizzy at times - and I still have that 'metallic' taste. However, things are changing and are moving in the right direction... I'm feeling better every day. Recently a friend asked if I'm OK now - I replied: No, but I'm rising above it until it goes away.My doc' doesn't think my condition is from Chantix, but... GET REAL: It only takes a small sample from the internet community and other personal friends to prove him wrong. I personally know several people that have quit with Chantix with no complaints... Some are now smoke-free/same, but Some are smoke-free/different.For the record, I was never diagnosed with any anxiety, depression or any other kind of thought-process handicap. I was not, nor had been on any type of medicine, maintenance drug or illicit drugs. I had a fear of heights and a fear of giving public speeches.This is only a small synopsis of what I've been through. I'm still recovering so I will be checking this site every once in a while - let me know if you have any questions.rkwa
Posted by: rkwa 2/21/2008 1:43:00 AM

I am a 34 year old male. I have been smoke free for over two months and off of Chantix just over a month. I stopped taking Chantix early because of anxiety attacks that I felt were caused from the Chantix. Now even though I have been off of Chantix for over a month I am still having constant anxiety problems and trouble sleeping. My doctor has tried a couple of other prescriptions to try to help but none seem to work (Lexapro made the anxiety worse and Clonazepam helps some but only short periods at a time). The anxiety still persist pretty much all the time. This is causing me to miss work and is very disruptive to my family life. It has become quite the chore to do even the most average day to day tasks. Is this just delayed nicotine withdrawl or Chantix withdrawl or has the Chantix somehow damaged my brain? I have been off Chantix since Feb 4. Is there any relief in the near future? Will I ever be normal again?
Posted by: Jason 3/5/2008 9:14:20 AM

I just started taking Chantix 2 weeks ago. I have yet to experience ANY side effects that have been mentioned throughout this post (i.e. nausea, vomiting, depression, insomnia, ect.). Knock on wood…The drug seems to be working fine and controlling my withdrawals within reason. I will continue to take the drug until I am 100% smoke free. Honestly though, I am extremely disappointed to hear of all the horrific stories some of you have experienced on or off Chantix. However, with that said, you have no one to blame but yourselves. Who started smoking in the first place? You did! We as smokers need to understand that it’s our own demons which cause our addiction. After trying anything to quit, we bitch and moan that it doesn’t work or it has adverse side effects. Did you expect it to make all your addictions disappear with no problems?? Is anything in life that easy?? If you weren’t expecting side effects from this drug then why did you even start smoking in the first place??? Now for the suicide issue… As a 26 (27 on Monday) year old who has smoked for 13 years, I have everything in the world to live for. A beautiful Fiancée, a wonderful family, a management position for a development and construction firm, a fully furnished condominium, a brand new Dodge Ram, 2 drum sets, an ATV, and a big screen LCD with a Playstaion 2. Why would I ever consider giving it all up?? I have never been depressed and never will be. There are way too many things in life to be thankful for. Especially your health!!! Everybody who is depressed because of this drug needs to be thankful for what they have…No matter how bad you have it, there is ALWAYS someone that has it worse.After losing an uncle to lung cancer, and my fiancée losing her aunt to lung cancer, it’s time to quit. I know firsthand the difficulty in trying to quit, and I will agree that yes, it is tough. But those of you that are dead set on quitting, why not try cold turkey? Why do you need something to assist you? If you are that set on quitting, then your will alone should be enough to make you quit. Simply put, a Self fulfilling prophecy…Maybe I have not been on it long enough to experience the full side effects produced. However, no matter what, under ANY circumstances would I EVER consider the thought of suicide…Those of you that have, well it sounds like you need psychiatric evaluation…Not an anti smoking drug
Posted by: Kevin 3/6/2008 9:01:06 AM

The post above being one of the most ignorant I have yet to read regarding the adverse effects of this drug. If these claims were unfounded, why would the FDA have already issued an early communication regarding these reactions in November of last, and a second public health warning about the suicidal thoughts, bizarre behaviour, and neuropsychiatric side effects being noted in people taking this drug. And their investigation is ongoing, which means there will be more to come as they evaluate the many many adverse reaction reports they have received. The last number I saw regarding the suicidal behaviour was 55 suicides. I am happy that you are not experiencing any of the adverse effects to date, but note that many are not having these reactions until after they stop the drug, and then the side effects are simply...not going away. I had never had any psychological disorders or depression or severe anxiety...in my life. Was a very happy content person with everything in my life when I started taking it. Discontinued on the 6th day due to an onset of joint pain, and 'went off the deep end' 2 days after that with thoughts of driving my car into oncoming traffic. It has taken a year for the joint pain to go away, and the mental hell I went through due to this drug was unfair, and I was not warned. Due to the large number of people reporting these types of reactions, at least Pfizer has updated their warnings so people may not be so blindsided as the first round of us guinea pigs were. Read some more about this drug, and you will see how very very lucky you are if you are able to complete your treatment, stop the drug, and not have any issues crop up. I do hope you are in that majority, the latter side is horrible.
Posted by: Brenda 3/7/2008 7:43:44 AM

Has any of you actually got back to "normal" after quitting Chantix? If so, how long did it take? It would be nice to know if the end of this anxiety ride is near but right now I just can't see the light at the end of the tunnel.
Posted by: Jason 3/14/2008 9:15:22 AM

Hey all, Holy Cow I am so upset that I didn't find this site BEFORE I started taking the Chantix... I have struggled with anxiety/panic for 10 years (but for the most part had it under control for that last 8 years) depression however has never really been a problem for me. I took the Chantix for 3 weeks and decided to stop taking it because it made me nauseous and I have stopped smoking with no desire to start again... well that did it. A day or 2 after I quit, I started having this foggy/fuzzy feeling kinda like I was more of a specator in my life than a participant. I was familiar with this feeling as I would experience this sensation when I was in a state of extreme anxiety. The only problem was I didn't feel anxious really, more tense than anything else. Within a day I began feeling really down - hopeless even. I was driving home from work and had this random thought that wrapping my car around a tree didn't sound so bad. DID THAT FREAK ME OUT!!! I went home and told my husband while I sobbed. He has been taking Chantix also and still is taking his... he doesn't understand because he doesn't feel this way. The last 2 days he has been having 5 nosebleeds per day... which would freak me out. Anyway, I feel sad and out of it everyday (this is while on 100mg of Zoloft as well) I'm going into day 9 off the medication and day 9 of feeling like crap. Please tell me that I will feel normal again... I have 4 little ones who need me.
Posted by: Liz 3/15/2008 7:56:00 AM

Hmm,Seems like Mr. Mar 6th may be a Pfizer rep/employ. Maybe not - Mr. Nar 5 - If your experience has been so good then why were you browsing here???Answer to the question: Will I ever be "normal" again - NO, because normal for You has been nicotine for decades. The question should be: "will I ever feel comfortable again", and the answer is yes - but it might take MONTHS (that's not that long considering 20/30yrs of nicotine).I actually smoked come cigarettes after my last post to see what would happen ( NOT RECOMMENDED - OW ). What I can tell you is that it was very enlightening. I initially felt horrible, but I did sleep better. Smoking 1 (one) a day for three days made it easier to cope - but then I felt the addiction coming back. So I quit immediately - but then had to suffer the horrible withdrawal all over again (this happened from just 1 smoke/day for only 3 days!!!).I truly believe this:This is all caused by the withdrawal from decades of addiction. Nicotine addiction is very, very complicated; even more so than that of any of the available anti-depressants. Getting back to "normal" depends on the individual and the circumstances - it may be like recovering from a stroke and require months, or it might be like recovering from a trauma and require weeks. However, you WILL get back. You need to let your brain assimilate and in the short term need to be strong enough to work through emotional conflicts and your short emotional fuse.By the way:For me it seems that any "mind-altering" drugs make the following days much worse (eg. nicotine, sleeping pills, anti-dep's, tranquilizers, OTC sleep aids, etc).Don't give up,rkwa
Posted by: rkwa 3/16/2008 11:51:29 AM

I was on Chantix for 30 days in late 2007. During that time I don't recall experiencing any side affects. After the first week, I not only stopped smoking but I never really had an overwhelming craving to light up. Prior to this, I had been a smoker for 6 or 7 years. On day 31, my prescription ran out, I didn't renew, and decided to light up mainly because old habits die hard.Just recently I have been re-diagnosed Bipolar by an actual psychotherapist. The first time was in 2002 but I had decided to stop treatment. I'm currently taking 300mg of Seroquel and have been doing so for almost 2 months. During these two months, I've had my dosage upped to 400mg and ultimately 600mg. Unfortunately, for the first time ever in my life, at those higher dosages, I had one too many episodes of full on panic attack, dementia, and what I suspect was postural hypotension. Hence, me dropping down to 300mg where I am stable.My point is, I have been suffering from bipolar disorder for years, and untreated, Chantix worked wonders for me. Now that I'm on medication and the door has been opened for anxiety attacks, I'm not sure I am willing to personally find out what this mixture of the two medications will cause.
Posted by: Mike 4/12/2008 7:35:26 AM

I have been smoking for 40 years and nothing worked before chantix. Does it have side effects? Yes, it does. I did not experience any depression or suicidal thoughts whatsoever. The drug did make me nausceous, gave me heartburn and upset my GI track. I continued the drug for two months even though I had these side effects. My Doctor had told me to try and get through this discomfort. In other words, he would have me nauseous rather than smoke. I stayed with it like he suggested and finally after two months, my stomach was really really bad.By then, I had quit smoking completely.I am 3 months smoke free and will NEVER go back. I do not want to ever go through that process again.I still say Chantix was worth it for me because it worked despite the side effects.
Posted by: Carol 4/16/2008 8:05:51 AM



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